A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
NCT05592626
This study is recruiting at 10 US sites in 9 states, according to its ClinicalTrials.gov record last updated .
Summary
This is an open label, multicenter, phase 1/2 study to assess the safety/tolerability and preliminary clinical activity of STAR0602 as a single agent and in combination with chemotherapy administered intravenously in participants with advanced solid tumors that are antigen-rich.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Advanced Solid Tumors
- Genital Neoplasm, Female
- Urogenital Neoplasms
- Lung Neoplasm
- Neoplasms by Site
- Papillomavirus Infection
- Epstein-Barr Virus Infections
- Carcinoma
- Neoplasms
- Vulvar Neoplasms
- Vulvar Diseases
- Abdominal Neoplasm
- NSCLC (Non-small Cell Lung Cancer)
- Colorectal Cancer
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 1/2
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Marengo Therapeutics, Inc.
- Last updated on ClinicalTrials.gov
- August 11, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Florida · 1
- AdventHealth Celebration · Celebration, FL
Kansas · 1
- The University of Kansas Cancer Center · Kansas City, KS
Maryland · 1
- National Institutes of Health · Bethesda, MD
Massachusetts · 1
- Massachusetts General Hospital Cancer Center · Boston, MA
Michigan · 1
- Karmanos Cancer Institute · Detroit, MI
Ohio · 1
- The Ohio State University Comprehensive Cancer Center · Columbus, OH
Tennessee · 1
- Sarah Cannon Research Institute Oncology Partners (SCRI-Nashville) · Nashville, TN
Texas · 2
- The University of Texas, MD Anderson Cancer Center · Houston, TX
- UT Health Mays Cancer Center · San Antonio, TX
Wisconsin · 1
- University of Wisconsin- Madison · Madison, WI
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.