The ED-AWARENESS-2 Trial
NCT05534243
This study is recruiting at 4 US sites in 4 states, according to its ClinicalTrials.gov record last updated .
Summary
The investigators will screen all mechanically ventilated ED patients for study eligibility and will enroll all consecutive patients satisfying inclusion and exclusion criteria. The study design is a pragmatic, multicenter, stepped wedge cluster randomized trial, enrolling at five sites over a 3-year period, divided into six time periods of six months. Prior to the study, each site will be randomized to their position within the design. One site will cross to the intervention period (i.e. succinylcholine as default neuromuscular blocker) every six months from the 2nd to 6th time period.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Awareness
- Mechanical Ventilation
- Intubation Complication
- PTSD
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Not applicable
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Washington University School of Medicine
- Last updated on ClinicalTrials.gov
- October 13, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Iowa · 1
- Roy J. and Lucille A. Carver College of Medicine · Iowa City, IA
Minnesota · 1
- Hennepin Healthcare · Minneapolis, MN
New Jersey · 1
- Cooper University Hospital/Cooper Medical School of Rowan University · Camden, NJ
Washington · 1
- University of Washington School of Medicine · Seattle, WA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.