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A Study of EP0031 (Lunbotinib) in Patients With Advanced RET-altered Malignancies

NCT05443126

This study is recruiting at 15 US sites in 11 states, according to its ClinicalTrials.gov record last updated .

Summary

The aim of this study is to assess the safety, side effects and effectiveness of EP0031 (Lunbotinib) in patients with advanced RET-altered non-small cell lung cancer (NSCLC) in monotherapy and in combination with standard of care (SOC) chemotherapy.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • NSCLC

Eligibility basics and study details

Study type
Interventional
Phase
Phase 1/2
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Ellipses Pharma
Last updated on ClinicalTrials.gov
July 1, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 2

  • David Geffen School of Medicine at UCLA · Los Angeles, CA
  • Stanford University · Stanford, CA

District of Columbia · 1

  • Georgetown University · Washington D.C., DC

Florida · 2

  • University of Miami - Sylvester Comprehensive Cancer Center · Miami, FL
  • Florida Cancer Specialists & Research Institute · West Palm Beach, FL

Illinois · 1

  • Northwestern University · Evanston, IL

Massachusetts · 1

  • Massachusetts General Hospital · Boston, MA

New York · 2

  • Memorial Sloan Kettering Cancer Center · New York, NY
  • NYU Langone Health · New York, NY

Ohio · 1

  • The Ohio State University - Comprehensive Cancer Center · Columbus, OH

Oregon · 1

  • Providence Portland Medical Centre · Portland, OR

Texas · 1

  • MD Anderson Cancer Center · Houston, TX

Virginia · 1

  • Virginia Cancer Specialists · Fairfax, VA

Washington · 2

  • University of Washington - Fred Hutchinson Cancer Center · Seattle, WA
  • Washington University - School of Medicine · Seattle, WA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.