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Decoding and Modulating Affective Brain States

NCT05437705

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

The research study is being conducted to study brain patterns of negative emotion and develop personalized brain stimulation protocols to disrupt these patterns with transcranial magnetic stimulation (TMS). First, the investigators will use functional Magnetic Resonance Imaging (fMRI) data to generate a negative affect map for each participant.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Rumination
  • Major Depressive Disorder
  • Anxiety

Eligibility basics and study details

Study type
Interventional
Phase
Not applicable
Ages
18 to 65 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
University of Pennsylvania
Last updated on ClinicalTrials.gov
September 3, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Pennsylvania · 1

  • University of Pennsylvania · Philadelphia, PA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.