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Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents

NCT05437588

This study is recruiting at 2 US sites in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

This study is dedicated to help identify biomarkers for depression and suicide. The purpose of the study is to better understand these links to improve medical and psychiatric care in the future. This research is also to test the effects of standard treatment of depression on improvement in depressive and suicidal behavior and on biomarkers (e.g. miRNA) for these disorders.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Major Depressive Disorder
  • Suicidal Ideas
  • Suicide, Attempted
  • MDD
  • Depression
  • Depression, Teen
  • Depression and Suicide
  • Depression in Adolescence
  • Suicide

Eligibility basics and study details

Study type
Interventional
Phase
Not applicable
Ages
10 to 24 years
Sex
All
Healthy volunteers
Accepted
Sponsor
University of Alabama at Birmingham
Last updated on ClinicalTrials.gov
July 13, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Alabama · 2

  • University of Alabama at Birmingham · Birmingham, AL
  • UAB Huntsville Regional Medical Campus · Huntsville, AL

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.