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A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

NCT05361174

This study is recruiting at 10 US sites in 7 states, according to its ClinicalTrials.gov record last updated .

Summary

This is a study to investigate the efficacy and safety of an infusion of IOV-4001 in adult participants with unresectable or metastatic melanoma or advanced non-small-cell lung cancer (NSCLC).

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Unresectable Melanoma
  • Metastatic Melanoma
  • Stage III Non-small Cell Lung Cancer
  • Stage IV Non-small Cell Lung Cancer

Eligibility basics and study details

Study type
Interventional
Phase
Phase 1/2
Ages
18 to 70 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
Iovance Biotherapeutics, Inc.
Last updated on ClinicalTrials.gov
June 11, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 1

  • The Angeles Clinic and Research Institute · Los Angeles, CA

Florida · 3

  • Sylvester Comprehensive Cancer Center · Miami, FL
  • Orlando Health Cancer Institute · Orlando, FL
  • Moffitt Cancer Center · Tampa, FL

Kansas · 1

  • The University of Kansas Cancer Center · Westwood, KS

Kentucky · 1

  • University of Louisville · Louisville, KY

New York · 2

  • Memorial Sloan Kettering Cancer Center · New York, NY
  • Weill Medical College of Cornell University · New York, NY

Ohio · 1

  • University of Cincinnati · Cincinnati, OH

Pennsylvania · 1

  • UPMC Hillman Cancer Center · Pittsburgh, PA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.