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AOH1996 for the Treatment of Refractory Solid Tumors

NCT05227326

This study is recruiting at 2 US sites in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

This phase I trial studies the side effects and best dose of AOH1996 in treating patients with solid tumors that do not respond to treatment (refractory). AOH1996 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Refractory Malignant Solid Neoplasm
  • Osteosarcoma
  • Leiomyosarcomas
  • Synovial Sarcomas
  • Ovarian Cancer
  • Non-Small Cell Lung Cancer
  • Pancreatic Cancer

Eligibility basics and study details

Study type
Interventional
Phase
Phase 1
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
City of Hope Medical Center
Last updated on ClinicalTrials.gov
July 28, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 2

  • City of Hope Medical Center · Duarte, CA
  • City of Hope at Long Beach Elm · Long Beach, CA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.