VIBRANT: VIB4920 for Active Lupus Nephritis
NCT05201469
This study is recruiting at 15 US sites in 10 states, according to its ClinicalTrials.gov record last updated .
Summary
This is a multi-center double-blind placebo controlled clinical trial evaluating the efficacy of VIB4920 combined with mycophenolate mofetil (MMF) and prednisone in achieving a renal response in participants with active lupus nephritis (LN).
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Lupus Nephritis
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 2
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- Last updated on ClinicalTrials.gov
- September 16, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
California · 4
- University of California San Diego School of Medicine: Division of Rheumatology, Allergy and Immunology · La Jolla, CA
- UCLA Medical Center: Division of Rheumatology · Los Angeles, CA
- of California, Irvine School of Medicine Division of Rheumatology · Orange, CA
- University of California San Francisco School of Medicine: Lupus Clinic and Rheumatology Clinical Research Center · San Francisco, CA
Colorado · 1
- University of Colorado School of Medicine: Division of Rheumatology · Aurora, CO
Florida · 1
- University of Miami Miller School of Medicine: Nephrology & Hypertension Division · Miami, FL
Georgia · 1
- Emory University School of Medicine: Division of Rheumatology · Atlanta, GA
Illinois · 1
- University of Chicago, Department of Medicine: Rheumatology · Chicago, IL
Michigan · 1
- University of Michigan · Ann Arbor, MI
Missouri · 1
- Washington University School of Medicine in St. Louis: Division of Nephrology · St Louis, MO
New York · 2
- Feinstein Institute for Medical Research: Center for Autoimmune and Musculoskeletal Diseases · Manhasset, NY
- Columbia University Medical Center: Department of Medicine, Division of Rheumatology · New York, NY
Pennsylvania · 2
- Penn State Health Milton S. Hershey Medical Center: Division of Rheumatology · Hershey, PA
- Temple University, Lewis Katz School of Medicine, Department of Medicine: Nephrology · Philadelphia, PA
South Carolina · 1
- University of South Carolina · Charleston, SC
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.