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Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer

NCT05061550

This study is recruiting at 18 US sites in 14 states, according to its ClinicalTrials.gov record last updated .

Summary

The study is intended to assess the safety and efficacy of perioperative treatment with Durvalumab in combination with Oleclumab, Monalizumab, or AZD0171 and platinum doublet chemotherapy (CTX); or Volrustomig or Rilvegostomig in combination with CTX; or Datopotamab deruxtecan (Dato-DXd) in combination with Durvalumab or Rilvegostomig and single agent platinum chemotherapy in participants with resectable, early-stage non-small cell lung cancer.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Non-small Cell Lung Cancer

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2
Ages
18 to 95 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
AstraZeneca
Last updated on ClinicalTrials.gov
September 23, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Arkansas · 1

  • Research Site · Little Rock, AR

California · 1

  • Research Site · Los Angeles, CA

Connecticut · 1

  • Research Site · New Haven, CT

Illinois · 1

  • Research Site · Chicago, IL

Maryland · 1

  • Research Site · Baltimore, MD

Massachusetts · 1

  • Research Site · Boston, MA

Nebraska · 1

  • Research Site · Omaha, NE

New York · 1

  • Research Site · Buffalo, NY

Ohio · 1

  • Research Site · Cleveland, OH

Pennsylvania · 1

  • Research Site · Pittsburgh, PA

Tennessee · 4

  • Research Site · Chattanooga, TN
  • Research Site · Memphis, TN
  • Research Site · Nashville, TN
  • Research Site · Nashville, TN

Texas · 1

  • Research Site · Houston, TX

Virginia · 1

  • Research Site · Fairfax, VA

Washington · 2

  • Research Site · Edmonds, WA
  • Research Site · Seattle, WA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.