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A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

NCT04928846

This study is recruiting at 9 US sites in 5 states, according to its ClinicalTrials.gov record last updated .

Summary

Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. Non-small cell lung cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. The purpose of this study is to determine if telisotuzumab vedotin works better than docetaxel and to assess how safe telisotuzumab vedotin is in adult participants with NSCLC who have previously been treated. Change in disease activity and adverse events will be assessed. Telisotuzumab vedotin is an investigational drug being developed for the treatment of NSCLC.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Non Small Cell Lung Cancer
  • c-MET

Eligibility basics and study details

Study type
Interventional
Phase
Phase 3
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
AbbVie
Last updated on ClinicalTrials.gov
October 5, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 4

  • City of Hope /ID# 243157 · Duarte, CA
  • City Of Hope - Seacliff /ID# 263143 · Huntington Beach, CA
  • City of Hope - Orange County Lennar Foundation Cancer Center /ID# 263144 · Irvine, CA
  • City Of Hope - Antelope Valley /ID# 263138 · Lancaster, CA

Hawaii · 1

  • Kaiser Permanente Moanalua Medical Center /ID# 238363 · Honolulu, HI

Mississippi · 1

  • Hattiesburg Clinic /ID# 248033 · Hattiesburg, MS

Missouri · 2

  • St. Lukes Hosp. of Kansas City /ID# 259940 · Kansas City, MO
  • Hulston Cancer Center /ID# 232226 · Springfield, MO

Washington · 1

  • Valley Medical Center /ID# 253950 · Renton, WA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.