Ferric Citrate and Chronic Kidney Disease in Children
NCT04741646
This study is recruiting at 16 US sites in 9 states, according to its ClinicalTrials.gov record last updated .
Summary
We will conduct a 12-month, double-blind, randomized, placebo-controlled trial to assess the effects of therapy with ferric citrate (FC) on changes in intact FGF23 levels (iFGF23, primary endpoint) in 160 pediatric patients (80 in each of the two arms) aged 6-18 years of either sex with chronic kidney disease (CKD) stages 3-4 and age-appropriate normal serum phosphate levels. Participants will be randomized to one of the two groups: 1) FC or 2) FC placebo. Participants will be recruited from 20 core clinical sites.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Chronic Kidney Diseases
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 2
- Ages
- 6 to 18 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- University of California, Los Angeles
- Last updated on ClinicalTrials.gov
- April 17, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
California · 3
- University of California, Los Angeles · Los Angeles, CA
- Children's Hospital of Orange County · Orange, CA
- University of California, San Francisco · San Francisco, CA
Florida · 1
- Arnold Palmer Hospital for Children · Orlando, FL
Georgia · 1
- Emory University · Atlanta, GA
Indiana · 1
- Indiana U · Indianapolis, IN
Missouri · 2
- Children's Mercy Hospital, Kansas City · Kansas City, MO
- Washington U · St Louis, MO
New York · 2
- Cohen's Childrens · New York, NY
- Children's Hospital at Montefiore · The Bronx, NY
Ohio · 2
- Cincinnati Children's Hospital Medical Center · Cincinnati, OH
- Nationwide Children's · Columbus, OH
Pennsylvania · 1
- Children's Hospital of Philadelphia · Philadelphia, PA
Texas · 3
- Children's Medical Center, Dallas · Dallas, TX
- Baylor College of Medicine · Houston, TX
- UTH · Houston, TX
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.