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Early Life Stress and Depression: Molecular and Functional Imaging

NCT04713722

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

Severe childhood adversity accounts for a large portion of psychiatric illness, and an increased risk for major depressive disorder (MDD). For some individuals, childhood adversity has negative psychological and medical consequences; others preserve mental and physical health despite such experiences (they are resilient). In spite of this, little is known about the neurobiological mechanisms related to childhood adversity, especially oxidative stress abnormalities in the brain.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Depression
  • Trauma, Psychological

Eligibility basics and study details

Study type
Observational
Phase
Not applicable
Ages
20 to 32 years
Sex
Female
Healthy volunteers
Accepted
Sponsor
Mclean Hospital
Last updated on ClinicalTrials.gov
December 12, 2025

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Massachusetts · 1

  • McLean Hospital · Belmont, MA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.