A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
NCT04657068
This study is recruiting at 38 US sites in 21 states, according to its ClinicalTrials.gov record last updated .
Summary
This clinical trial is evaluating a drug called ART0380 in participants with advanced or metastatic solid tumors. The main goals of this study are to: Find the recommended dose of ART0380 that can be given safely to participants alone and in combination with gemcitabine or irinotecan Learn more about the side effects of ART0380 alone and in combination with gemcitabine or irinotecan Learn more about the effectiveness of ART0380 alone and in combination with gemcitabine or irinotecan
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Advanced Cancer
- Metastatic Cancer
- Ovarian Cancer
- Primary Peritoneal Cancer
- Fallopian Tube Cancer
- Endometrial Cancer
- Metastatic Colorectal Cancer
- Pancreatic Ductal Adenocarcinoma
- Acinar Cell Carcinoma
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 1/2
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Artios Pharma Ltd
- Last updated on ClinicalTrials.gov
- July 30, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- University of Alabama at Birmingham · Birmingham, AL
Arizona · 1
- Mayo Clinic (Arizona) · Scottsdale, AZ
Arkansas · 1
- University of Arkansas - Winthrop P. Rockefeller Cancer Institute · Little Rock, AR
California · 3
- USC Norris Comprehensive Cancer Center · Los Angeles, CA
- Sansum Clinic · Santa Barbara, CA
- Providence Medical Foundation · Santa Rosa, CA
Colorado · 2
- Rocky Mountain Cancer Center · Denver, CO
- Sarah Cannon Research Institute at HealthONE · Denver, CO
Florida · 5
- Florida Cancer Specialists · Fort Myers, FL
- Cancer Specialists of North Florida · Jacksonville, FL
- Mayo Clinic (Florida) · Jacksonville, FL
- Florida Cancer Specialists · Sarasota, FL
- Florida Cancer Specialists · West Palm Beach, FL
Illinois · 1
- Hope and Healing Cancer Services · Hinsdale, IL
Indiana · 1
- Community Health Network · Indianapolis, IN
Louisiana · 1
- Our Lady of the Lake · Baton Rouge, LA
Maryland · 1
- Maryland Oncology Hematology - Primary · Columbia, MD
Minnesota · 2
- Minnesota Oncology Hematology · Maple Grove, MN
- Mayo Clinic (Minnesota) · Rochester, MN
Missouri · 1
- Washington University · St Louis, MO
New York · 2
- Hematology Oncology Associates of Central New York · East Syracuse, NY
- Northwell Health Cancer Institute · Lake Success, NY
Ohio · 2
- Oncology Hematology Care Primary · Cincinnati, OH
- Taylor Cancer Research Center · Maumee, OH
Oklahoma · 1
- Stephenson Cancer Center · Oklahoma City, OK
Oregon · 1
- Oregon Health & Science University · Portland, OR
Pennsylvania · 2
- Thomas Jefferson University, Sidney Kimmel Cancer Center, Clinical Research Organization · Philadelphia, PA
- University of Pennsylvania / Abramson Cancer Center · Philadelphia, PA
Tennessee · 3
- Tennessee Oncology, PLLC · Chattanooga, TN
- SCRI Oncology Partners · Nashville, TN
- Vanderbilt Medical Center · Nashville, TN
Texas · 5
- Texas Oncology - Central/South Texas · Austin, TX
- Mary Crowley Cancer Research · Dallas, TX
- Texas Oncology - Baylor Charles A. Sammons Cancer Center · Dallas, TX
- Texas Oncology - Northeast Texas · Flower Mound, TX
- Texas Oncology - San Antonio · San Antonio, TX
Utah · 1
- Utah Cancer Specialists · Salt Lake City, UT
Virginia · 1
- Virginia Cancer Specialists · Fairfax, VA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.