Study of PF-07248144 in Advanced or Metastatic Solid Tumors
NCT04606446
This study is recruiting at 21 US sites in 6 states, according to its ClinicalTrials.gov record last updated .
Summary
This is an open-label, multi center study to evaluate safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of PF-07248144 and early signs of clinical efficacy of PF-07248144 as a single agent and in combination with other agents
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Locally Advanced or Metastatic ER+ HER2- Breast Cancer
- Locally Advanced or Metastatic Castration-resistant Prostate Cancer
- Locally Advanced or Metastatic Non-small Cell Lung Cancer
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 2
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Pfizer
- Last updated on ClinicalTrials.gov
- April 16, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
California · 3
- Cedars Sinai Medical Center · Los Angeles, CA
- Cedars-Sinai Cancer at Cedars-Sinai Medical Center · Los Angeles, CA
- UCSF Medical Center at Mission Bay · San Francisco, CA
Connecticut · 4
- Smilow Cancer Hospital at Yale - New Haven · New Haven, CT
- Smilow Cancer Hospital Phase 1 Unit · New Haven, CT
- Yale University · New Haven, CT
- Yale-New Haven Hospital- Yale Cancer Center · New Haven, CT
Kentucky · 4
- St. Elizabeth Healthcare · Edgewood, KY
- University Medical Center, lnc.:DBA University of Louisville Hospital · Louisville, KY
- University of Louisville · Louisville, KY
- UofL Health Brown Cancer Center · Louisville, KY
Tennessee · 1
- SCRI Oncology Partners · Nashville, TN
Texas · 7
- MD Anderson The Woodlands · Conroe, TX
- MD Anderson West Houston · Houston, TX
- The University of Texas M. D. Anderson Cancer Center · Houston, TX
- U.T. MD Anderson Cancer Center · Houston, TX
- MD Anderson League City · League City, TX
- NEXT Oncology · San Antonio, TX
- MD Anderson · Sugar Land, TX
Washington · 2
- Swedish Cancer Institute · Seattle, WA
- Swedish Medical Center · Seattle, WA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.