A Randomized Trial to Evaluate Sequential vs Simultaneous Patching
NCT04378790
This study is recruiting at 68 US sites in 28 states, according to its ClinicalTrials.gov record last updated .
Summary
A randomized trial to determine whether simultaneous treatment with spectacles and patching has an equivalent VA outcome compared with sequential treatment, first with spectacles alone followed by patching (if needed), for previously untreated amblyopia in children 3 to <13 years of age.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Amblyopia
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 3 to 13 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Jaeb Center for Health Research
- Last updated on ClinicalTrials.gov
- February 11, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 2
- UAB Pediatric Eye Care; Birmingham Health Care · Birmingham, AL
- University of Alabama at Birmingham · Birmingham, AL
Arizona · 3
- Midwestern University Eye Institute · Glendale, AZ
- Arizonia Pediatric Eye Specialists · Phoenix, AZ
- University of Arizona · Tucson, AZ
California · 9
- Univ. of California- Berkeley · Berkeley, CA
- Marshall B. Ketchum University · Fullerton, CA
- Univ of California, Irvine- Gavin Herbert Eye Institute · Irvine, CA
- Loma Linda University Health Care, Dept. of Ophthalmology · Loma Linda, CA
- Children's Hospital of Los Angeles (CHLA) · Los Angeles, CA
- Stanford University · Palo Alto, CA
- Western University College of Optometry · Pomona, CA
- University of California, Davis · Sacramento, CA
- University of California San Francisco Department of Ophthalmology · San Francisco, CA
Connecticut · 1
- Eye Physicians & Surgeons, PC · Milford, CT
Florida · 3
- Nova Southeastern University College of Optometry, The Eye Institute · Fort Lauderdale, FL
- Nemours Children's Clinic · Jacksonville, FL
- University of South Florida (USF) Eye · Tampa, FL
Idaho · 1
- St Luke's Hospital · Boise, ID
Illinois · 4
- Ann & Robert H. Lurie Children's Hospital of Chicago · Chicago, IL
- Ticho Eye Associates · Chicago Ridge, IL
- Midwestern U Chicago College of Optometry · Downers Grove, IL
- Progressive Eye Care · Lisle, IL
Indiana · 2
- Indiana School of Optometry · Bloomington, IN
- Indiana University School of Optometry · Indianapolis, IN
Iowa · 1
- Wolfe Eye Clinic · West Des Moines, IA
Maryland · 1
- Wilmer Eye Institute · Baltimore, MD
Massachusetts · 2
- Boston Children's Hospital Waltham · Boston, MA
- Boston Medical Center · Boston, MA
Michigan · 2
- Corewell Health · Grand Rapids, MI
- Pediatric Ophthalmology, P.C. · Grand Rapids, MI
Minnesota · 3
- Zenith Vision Development Center · Duluth, MN
- Mayo Clinic · Rochester, MN
- PineCone Vision Center · Sartell, MN
Missouri · 3
- Children's Mercy Hospitals and Clinics · Kansas City, MO
- St. Louis Children's Hospital Eye Center · St Louis, MO
- U of MO St. Louis College of Optometry · St Louis, MO
Nebraska · 1
- University of Nebraska Medical Center · Omaha, NE
New York · 3
- Ross Eye Institute, University of Buffalo, Med School Dept Ophthalmology · Buffalo, NY
- NYU Langone Health · New York, NY
- State University of New York, College of Optometry · New York, NY
North Carolina · 2
- University of North Carolina · Chapel Hill, NC
- Duke University Eye Center · Durham, NC
Ohio · 3
- Akron Children's Hospital · Akron, OH
- Cincinnati Children's Hospital · Cincinnati, OH
- Ohio State University College of Optometry · Columbus, OH
Oklahoma · 1
- Dean A. McGee Eye Institute · Oklahoma City, OK
Oregon · 2
- River View Family Eyecare · Albany, OR
- Casey Eye Institute · Portland, OR
Pennsylvania · 5
- Pediatric Ophthalmology of Erie · Erie, PA
- Conestoga Eye · Lancaster, PA
- Salus University/Pennsylvania College of Optometry · Philadelphia, PA
- Wills Eye Hospital · Philadelphia, PA
- UPMC Children's Eye Center of Children's Hospital of Pittsburgh · Pittsburgh, PA
South Carolina · 1
- Prisma Health · Columbia, SC
Tennessee · 2
- Southern College of Optometry · Memphis, TN
- Vanderbilt University Medical Center - Vanderbilt Eye Institute · Nashville, TN
Texas · 6
- Pediatric Eye Specialists, LLP · Fort Worth, TX
- Baylor College of Medicine · Houston, TX
- Texas Tech University Health Science Center · Lubbock, TX
- San Antonio Eye Center · San Antonio, TX
- University of Incarnate Word Rosenberg School of Optometry · San Antonio, TX
- University of the Incarnate Word · San Antonio, TX
Utah · 1
- Rocky Mountain Eye Care Associates · Salt Lake City, UT
Virginia · 1
- Virginia Pediatric Eye Center · Norfolk, VA
Washington · 2
- Seattle Children's Hospital, University of Washington · Seattle, WA
- Spokane Eye Clinical Research · Spokane, WA
Wyoming · 1
- Snowy Range Vision Center · Laramie, WY
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.