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Blood Pressure Slopes and Ultrafiltration in Hemodialysis Patients

NCT04163614

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

Kidney failure has been recognized as one of the most costly chronic conditions among United States Veterans. Approximately 13,000 Veterans develop kidney failure each year, and most require hemodialysis initiation. Hemodialysis patients suffer significantly increased risk of death and hospitalizations, and excessive body fluid is a major cause of this. While empiric aggressive fluid removal during dialysis is one approach to limit fluid overload, this can cause dangerous decreases in blood pressure during dialysis that independently contribute to the high death rate.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • End Stage Renal Disease
  • Hypertension
  • Extracellular Volume Overload
  • Intradialytic Hypotension

Eligibility basics and study details

Study type
Interventional
Phase
Not applicable
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
VA Office of Research and Development
Last updated on ClinicalTrials.gov
July 20, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Texas · 1

  • VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX · Dallas, TX

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.