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Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial

NCT03990896

This study is recruiting at 7 US sites in 7 states, according to its ClinicalTrials.gov record last updated .

Summary

This research is to evaluate the effectiveness of Talazoparib as a potential treatment for metastatic breast cancer with a BRCA 1 or BRCA 2 mutation.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Breast Cancer

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2
Ages
18 years and older
Sex
Female
Healthy volunteers
Not accepted
Sponsor
Massachusetts General Hospital
Last updated on ClinicalTrials.gov
May 6, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 1

  • UCSF Medical Center-Mission Bay/Benioff Children's Hospital · San Francisco, CA

Georgia · 1

  • Emory University Winship Cancer Institute · Atlanta, GA

Illinois · 1

  • Northwestern University · Chicago, IL

Massachusetts · 1

  • Massachusetts General Hospital Cancer Center · Boston, MA

New York · 1

  • Weill Cornell Medicine · New York, NY

Tennessee · 1

  • Vanderbilt University · Nashville, TN

Texas · 1

  • MD Anderson Cancer Center · Houston, TX

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.