Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
NCT03907046
This study is recruiting at 142 US sites in 39 states, according to its ClinicalTrials.gov record last updated .
Summary
Primary Aim: To determine if apixaban is superior to aspirin for prevention of the composite outcome of any stroke (hemorrhagic or ischemic) or death from any cause in patients with recent ICH and atrial fibrillation (AF). Secondary Aim: To determine if apixaban, compared with aspirin, results in better functional outcomes as measured by the modified Rankin Scale.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Intracerebral Hemorrhage
- Atrial Fibrillation
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Yale University
- Last updated on ClinicalTrials.gov
- May 8, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 2
- University of Alabama Hospital · Birmingham, AL
- University of South Alabama University Hospital · Mobile, AL
Arizona · 1
- Banner University Medical Center · Tucson, AZ
California · 19
- Mercy San Juan Medical Center · Carmichael, CA
- Arrowhead Regional Medical Center · Colton, CA
- Kaiser Permanente Fontana Medical Center · Fontana, CA
- Community Regional Medical Center of Fresno · Fresno, CA
- St. Jude Medical Center · Fullerton, CA
- Los Alamitos Medical Center · Los Alamitos, CA
- Cedars-Sinai Medical Center · Los Angeles, CA
- Kaiser Permanente Los Angeles Medical Center · Los Angeles, CA
- Ronald Reagan UCLA Medical Center · Los Angeles, CA
- Doctors Medical Center Modesto, Modesto, CA · Modesto, CA
- UC Irvine Medical Center · Orange, CA
- Desert Regional Medical Center · Palm Springs, CA
- Kaiser Permanente Redwood City Medical Center, Redwood City, CA · Redwood City, CA
- Kaiser Permanente Sacramento Medical Center · Sacramento, CA
- UC Davis Medical Center · Sacramento, CA
- San Francisco General Hospital · San Francisco, CA
- Santa Barbara Cottage Hospital · Santa Barbara, CA
- Stanford University Medical Center · Stanford, CA
- PIH Health Hospital - Whittier · Whittier, CA
Colorado · 1
- University of Colorado Hospital · Aurora, CO
Connecticut · 2
- Hartford Hospital · Hartford, CT
- Yale New Haven Hospital · New Haven, CT
Delaware · 1
- New Hanover Regional Medical Center · Wilmington, DE
District of Columbia · 2
- George Washington University Hospital · Washington D.C., DC
- MedStar Georgetown University Hospital · Washington D.C., DC
Florida · 8
- Morton Plant Hospital · Clearwater, FL
- Broward Health Medical Center · Fort Lauderdale, FL
- UF Health Jacksonville · Jacksonville, FL
- Jackson Memorial Hospital · Miami, FL
- Ascension Sacred Heart Pensacola · Pensacola, FL
- Cleveland Clinic Tradition Hospital · Port Saint Lucie, FL
- St. Joseph's Hospital · Tampa, FL
- Tampa General Hospital · Tampa, FL
Georgia · 4
- Emory University Hospital · Atlanta, GA
- Grady Memorial Hospital · Atlanta, GA
- Augusta University Medical Center · Augusta, GA
- WellStar Kennestone Hospital · Marietta, GA
Hawaii · 1
- The Queen's Medical Center · Honolulu, HI
Idaho · 1
- Saint Alphonsus Regional Medical Center - Boise · Boise, ID
Illinois · 8
- NCH Hospital, Arlington Heights · Arlington Heights, IL
- Rush University Medical Center · Chicago, IL
- University of Chicago Medical Center · Chicago, IL
- University of Illinois Hospital · Chicago, IL
- Evanston Hospital · Evanston, IL
- Loyola University Medical Center · Maywood, IL
- OSF St. Francis Medical Center · Peoria, IL
- Central DuPage Hospital · Winfield, IL
Indiana · 1
- IU Health Methodist Hospital · Indianapolis, IN
Iowa · 1
- University of Iowa Medical Center · Iowa City, IA
Kansas · 1
- University of Kansas Hospital · Kansas City, KS
Kentucky · 3
- Baptist Health Lexington · Lexington, KY
- University of Kentucky Hospital · Lexington, KY
- University of Louisville Hospital · Louisville, KY
Louisiana · 1
- Ochsner Medical Center - Main Campus · New Orleans, LA
Maine · 1
- Maine Medical Center · Portland, ME
Massachusetts · 7
- Beth Israel Deaconess Medical Center · Boston, MA
- Boston Medical Center · Boston, MA
- Massachusetts General Hospital · Boston, MA
- Tufts Medical Center · Boston, MA
- Lahey Hospital & Medical Center · Burlington, MA
- Baystate Medical Center · Springfield, MA
- UMass Memorial Medical Center · Worcester, MA
Michigan · 2
- Trinity Health Saint Mary's · Grand Rapids, MI
- Munson Medical Center · Traverse City, MI
Minnesota · 3
- Abbott Northwestern Hospital · Minneapolis, MN
- M Health Fairview University of Minnesota Medical Center · Minneapolis, MN
- St. Cloud Hospital · Saint Cloud, MN
Missouri · 6
- University of Missouri Health Care · Columbia, MO
- Cox Medical Center South · Springfield, MO
- Mercy Hospital Springfield · Springfield, MO
- Barnes Jewish Hospital · St Louis, MO
- Mercy Hospital South · St Louis, MO
- Mercy Hospital St. Louis · St Louis, MO
Nebraska · 1
- University of Nebraska Medical Center · Omaha, NE
New Jersey · 5
- JFK Medical Center · Edison, NJ
- Hackensack University Medical Center · Hackensack, NJ
- Cooperman Barnabas Medical Center · Livingston, NJ
- Jersey Shore University Medical Center · Neptune City, NJ
- Overlook Medical Center · Summit, NJ
New York · 15
- Albany Medical Center · Albany, NY
- Kings County Hospital Center · Brooklyn, NY
- NYU Langone Hospital - Brooklyn · Brooklyn, NY
- NYC Health + Hospitals/Elmhurst · Elmhurst, NY
- North Shore University Hospital · Manhasset, NY
- Mount Sinai West · New York, NY
- NYP Columbia University Medical Center · New York, NY
- NYP Weill Cornell Medical Center · New York, NY
- The Mount Sinai Hospital · New York, NY
- Strong Memorial Hospital · Rochester, NY
- Stony Brook University Hospital · Stony Brook, NY
- SUNY Upstate Medical University · Syracuse, NY
- Montefiore Medical Center · The Bronx, NY
- Westchester Medical Center · Valhalla, NY
- Burke Rehabilitation Center · White Plains, NY
North Carolina · 8
- University of North Carolina Medical Center · Chapel Hill, NC
- Presbyterian Medical Center · Charlotte, NC
- Duke University Hospital · Durham, NC
- Moses H. Cone Memorial Hospital · Greensboro, NC
- ECU Health Medical Center · Greenville, NC
- New Hanover Regional Medical Center · Wilmington, NC
- Forsyth Medical Center · Winston-Salem, NC
- Wake Forest Baptist Medical Center · Winston-Salem, NC
Ohio · 8
- Cleveland Clinic Akron General · Akron, OH
- Good Samaritan Hospital · Cincinnati, OH
- University of Cincinnati Medical Center · Cincinnati, OH
- Cleveland Clinic · Cleveland, OH
- MetroHealth Medical Center · Cleveland, OH
- UH Cleveland Medical Center · Cleveland, OH
- OSU Wexner Medical Center · Columbus, OH
- Riverside Methodist Hospital · Columbus, OH
Oklahoma · 4
- Mercy Hospital Oklahoma City · Oklahoma City, OK
- OU Medical Center · Oklahoma City, OK
- Ascension St. John Medical Center · Tulsa, OK
- St. John Medical Center · Tulsa, OK
Oregon · 3
- Oregon Health & Science University Hospital · Portland, OR
- Providence St. Vincent Medical Center · Portland, OR
- PeaceHealth Sacred Heart Medical Center - RiverBend · Springfield, OR
Pennsylvania · 5
- Jefferson Abington Hospital · Abington, PA
- Penn State Hershey Medical Center · Hershey, PA
- Hospital of the University of Pennsylvania · Philadelphia, PA
- Temple University Hospital · Philadelphia, PA
- UPMC Presbyterian Hospital · Pittsburgh, PA
South Carolina · 2
- Medical University of South Carolina University Hospital · Charleston, SC
- Greenville Hospital System · Greenville, SC
South Dakota · 1
- Avera Research Institute · Sioux Falls, SD
Tennessee · 4
- Fort Sanders Regional Medical Center · Knoxville, TN
- Methodist University Hospital · Memphis, TN
- Semmes Murphey Main Campus · Memphis, TN
- Vanderbilt University Hospital · Nashville, TN
Texas · 3
- Houston Methodist Hospital · Houston, TX
- Memorial Hermann Texas Medical Center · Houston, TX
- University of Texas Health Science Center San Antonio · San Antonio, TX
Utah · 1
- University of Utah Healthcare · Salt Lake City, UT
Vermont · 1
- The University of Vermont Medical Center · Burlington, VT
Virginia · 3
- UVA Medical Center · Charlottesville, VA
- Inova Fairfax Hospital · Falls Church, VA
- Bon Secours St. Mary's Hospital · Richmond, VA
Washington · 1
- Harborview Medical Center · Seattle, WA
West Virginia · 1
- J.W. Ruby Memorial Hospital · Morgantown, WV
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.