Role of Genetic Factors in the Development of Lung Disease

Summary

This study is designed to evaluate the genetics involved in the development of lung disease by surveying genes involved in the process of breathing and examining the genes in lung cells of patients with lung disease. The study will focus on defining the distribution of abnormal genes responsible for processes directly involved in different diseases affecting the lungs of patients and healthy volunteers. Optional CT Sub-study The standard CT scan will be compared to the low dose radiation CT scan for the 150 subjects enrolled in the sub-study to assess the variation between the two techniques.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

• Cystic Fibrosis
• Pulmonary Fibrosis
• Tuberous Sclerosis
• Asthma
• Pulmonary Sarcoidosis

Eligibility basics and study details

Study type

Observational

Phase

Not applicable

Ages

2 to 90 years

Sex

All

Healthy volunteers

Accepted

Sponsor

National Heart, Lung, and Blood Institute (NHLBI)

Last updated on ClinicalTrials.gov

October 13, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites